Marion Downey, NDARC Communications Manager: Professor Shane Darke has recently completed a study which found a big increase in the number of sudden deaths and overdoses where the benzodiazepine alprazolam was involved. Professor Shane Darke: Benzodiazepines are tranquilisers and sleeping tablets. So people use them if for instance they have anxiety disorders, to calm them, or if they’re having trouble sleeping, to aid in sleep. Shane Darke: We did the study because we were seeing evidence amongst drug users, and there was also anecdotal evidence, that there was a problem with this particular drug. And we thought well, what we need to look at is – I suppose you could call it – the pointy end of this: is it being involved in deaths? What we looked at is every death going to the Department of Forensic Medicine in Sydney that had alprazolam detected in their blood. So this is any unnatural death or any sudden or unnatural death in which the drug was detected. Shane Darke: The main findings were there had been a major increase in the number of cases presenting with alprazolam and, more importantly, a major increase in the number of cases where alprazolam was contributing to death. By 2012, there were 86 cases, representing 1 in 20 cases that presented to the Department of Forensic Medicine. zoloft pfizer Xanax, a benzodiazepine prescription drug, is often used to aid in relieving symptoms like anxiety. Although the use of Xanax has been effective on countless occasions, the use of this drug is stirring up a number of concerns—one of the most severe being death caused by a Xanax overdose. Xanax is a schedule IV substance, which means it is only available through a physician but it also has a high risk for abuse and misuse. However, the illicit use of this drug is becoming more common—especially in teens and young adults. Benzodiazepine deaths accounted for roughly 9,000 deaths in 2015—showing an increase of almost five percent since 2002. Xanax is a popular prescription drug in the benzodiazepine class that was released in 1981 to treat panic disorders. Also known by its generic name, alprazolam, it works to depress the central nervous system and help reduce anxiety. Buy antabuse over counter See "General approach to drug poisoning in adults" and "Ethanol. Alprazolam is relatively more toxic than other benzodiazepines in. cialis l arginine Alprazolam, alprazolam toxicity, ards, benzodiazepine toxicity, benzodiazepines, bispectral index, cardiac, cardio-pulmonary support, care unit, critical care. The US Food and Drug Administration FDA reports in the prescribing information for Xanax that the maximum daily dose should not exceed 10 milligrams per. Xanax is an anti-anxiety drug – also known as a benzodiazepine, or benzo – that is used to help people with anxiety disorders or seizures. It is the brand name version of the generic drug alprazolam. Used under the advice of a doctor and as instructed, this substance is generally considered safe. Regular users develop tolerance and will require higher amounts of the drug over time to achieve the same effect as when they started using it. Many people who build tolerance to the drug also become dependent and may develop the type of compulsive use that characterizes addiction. Once a person has become dependent, it can be very risky to stop taking Xanax abruptly. These symptoms are not only uncomfortable, but can be dangerous or even deadly, especially in the case of long-term use or abuse of Xanax. The symptoms include: Seizures are the most dangerous symptom and can result in death. It is possible to minimize these symptoms and get through detox safely by working with a medical professional. Xanax is the brand name for alprazolam, a prescription medication used to treat anxiety and panic disorder. It’s possible to overdose on Xanax, especially if you take Xanax with other drugs or medications. Xanax is in a class of drugs known as benzodiazepines. These drugs work by boosting the activity of a chemical called gamma-aminobutyric acid (GABA) in the brain. GABA helps calm the nerves by inducing feelings of relaxation. Most severe or fatal overdoses happen when Xanax is taken with other drugs — especially opioid pain medications — or alcohol. If you’re taking Xanax, be sure to tell your doctor about any other medications you’re taking. The prescribed amount typically ranges from 0.25 to 0.5 milligrams (mg) per day. This amount may be split between three doses throughout the day. 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For help with Xanax abuse, call Black Bear Lodge.