Now, I have to deal with this sort of kidney pain and back pain everyday. I have been taking metformin for a week and have lost 19 pounds i am taking it for pcos and it has worked wonders i also have a normal cycle now i dont know if you have one or not but if you dont hopefully it will help I have been taking Metformn for over 3 years for my PCOS and never had an issue with kidney pain. I am on Synthoid, Metformin and Lovaza (basic Omega-3 acid to help lower triglycerides.) If the medication does not lower my level, should I ask the doctor to look at other underlining causes? Then when I got so sick had so many side effects I got scared that I might be doing damage to my already damaged liver. I have read that the metformin can cause liver and kidney damage so was worried about it, especially since my liver is damaged. I actually have had no problems at all taking it, I lost 50 lbs on it and stopped making cysts. my question to you is how much were you taking a day? I have taken Metformin 500 Mg x 2 times /day for nearly 3 years, but a year ago until now my feet are swollen, and I have bone spur on the left heel of my foot that is more growing bigger. Everyday when I take Metformin I usually have constipation and the top of my feet are swollen up. My fingers are so numb, and my urine is dark yellow and opaque. The results of the study indicated that the addition of metformin to peginterferon and ribavirin significantly decreased HOMA index at Week 24 and was associated with higher RVR rates vs placebo in these genotype 1 patients. amoxicillin whooping cough Rarely, too much metformin can build up in the body and cause a serious (sometimes fatal) condition called lactic acidosis. Lactic acidosis is more likely if you are an older adult, if you have kidney or liver disease, dehydration, heart failure, heavy alcohol use, if you have surgery, if you have X-ray or scanning procedures that use iodinated contrast, or if you are using certain drugs. For some conditions, your doctor may tell you to stop taking this medication for a short time. Stop taking this medication and get medical help right away if you have any symptoms of lactic acidosis, such as unusual tiredness, dizziness, severe drowsiness, chills, blue/cold skin, muscle pain, fast/difficult breathing, slow/irregular heartbeat, or stomach pain with nausea/vomiting/diarrhea. Show More Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb. Read the Patient Information Leaflet if available from your pharmacist before you start taking metformin and each time you get a refill. Sildenafil synthesis Viagra gГ©nГ©rique Diflucan oral suspension Initiation of metformin rather than a sulfonylurea as treatment for type 2 diabetes among patients with chronic kidney disease CKD is. levitra official website Background. Impaired renal function can lead to the accumulation of metformin, and elevated concentrations of metformin have been associated with lactic. Since metformin’s warning label is based, in part, on concerns about a different drug entirely, many researchers have tried to estimate how safe metformin is for people with diabetes whose kidney function is impaired. Metformin does not damage kidneys, that damage is done by high blood sugars. The biggest concern is when metformin is used and it doesn't adequately control blood sugars. In such case other medications or insulin should be started to get good blood sugar control. I have read that the metformin can cause liver and kidney damage so was worried about it, especially since my liver is damaged. The sooner blood sugars can be under tight control the better, as far as preventing / healing damage. Then when I got so sick had so many side effects I got scared that I might be doing damage to my already damaged liver. I have been taking metformin for a week and have lost 19 pounds i am taking it for pcos and it has worked wonders i also have a normal cycle now i dont know if you have one or not but if you dont hopefully it will help Metformin has been known to cause kidney and liver problems, but this does not happen in all patients, and there is some evidence there is a co-factor, in development of damage, such as alcoholism, or a combination of other drugs. All in all, the drug has a relatively good safety record. I would not fear taking Metformin if your physician recommends or concurs with your suggestion. I have taken Metformin 500 Mg x 2 times /day for nearly 3 years, but a year ago until now my feet are swollen, and I have bone spur on the left heel of my foot that is more growing bigger. Everyday when I take Metformin I usually have constipation and the top of my feet are swollen up. Metformin has actually brought a “black box” warning on its label — mandated by the U. Food and Drug Administration (FDA) — ever since it became available in the United States in 1994, due to concerns about lactic acidosis. This unusual however very serious response was found to be an unacceptably typical side effect of a drug associated to metformin — phenformin — which was pulled from the United States market in 1977. Lactic acidosis is much more typical in people with impaired kidney function. Since metformin’s warning label is based, in part, on issues about a various drug entirely, many scientists have actually attempted to approximate how safe metformin is for people with diabetes whose kidney function suffers. In 2015, we kept in mind that numerous researchers believe metformin is safe for individuals with mild to moderate kidney disease, defined as having an estimated glomerular purification rate (e GFR) of 30 — 60 ml/min. And one study found that using a safety cutoff of an e GFR of 30 ml/min, almost one million individuals in the United States who currently do not take metformin due to the fact that of the FDA’s labeling may be able to securely do so. The proof, it seems, has just grown more powerful in favor of metformin being more extensively prescribed to people with kidney disease. As kept in mind in a current post at Diabetes In Control.com, the blood-glucose-lowering advantages of loosening up limitations on metformin could be huge. Metformin kidney Can Metformin Increase Risk of Kidney Disease? - Type 2 Nation, Effect of metformin on kidney function in patients with type 2. Xanax is Metformin has traditionally been regarded as contraindicated in chronic kidney disease CKD, though guidelines in recent years have been relaxed to permit therapy if the glomerular filtration rate GFR is 30 mL/min. The main problem is the perceived risk of lactic acidosis LA. Metformin in Chronic Kidney Disease Time for a Rethink Metformin in People With Kidney Disease - Diabetes Self. Metformin Side Effects, Dosage & Uses - It can be hard on the kidneys, which is why those on Metformin have to have at least annual kidney function tests. This is what NICE has to say 1.6.22In adults with type 2 diabetes, review the dose of metformin if the estimated glomerular filtration rate eGFR is below 45 ml/minute/1.73m2 Stop metformin if the eGFR is below 30 ml/minute/1.73m2. valtrex and prednisone Caution Using Metformin For Patients With Reduced Kidney Function. Metformin, a first-line agent used in the treatment of type 2 diabetes. Metformin-associated lactic acidosis is exceedingly rare based on the available literature, and even though the use of metformin has not been comprehensively assessed in individuals with CKD, there is extensive evidence that this agent often is used without adverse effects in those with mildly to moderately reduced renal function.