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    Both ofloxacin and ciprofloxacin are fluoroquinolones with similar properties. However, antibiotics differ in their antimicrobial activity, clinical uses, pharmacokinetic and interaction profiles. Ciprofloxacin has better activity against Gram-negative bacilli. Ofloxacin has a longer half-life and higher serum levels. Ofloxacin does not significantly alter theophylline concentrations. Urinary tract infections Ciprofloxacin and ofloxacin are equally effective in women with complicated lower urinary tract infection Gonorrhea Single dose cefuroxime axetil is as effective as a single dose of ciprofloxacin in the treatment of uncomplicated gonorrhea caused by penicillinase-producing Neisseria gonorrhoeae (PPNG). However cefuroxime appears to be less effective than ciprofloxacin in treating urethral gonococcal infections in men, although both are highly effective in treating cervical gonococcal infections in women Skin infections Oral ciprofloxacin may be more effective than parenteral cefotaxime in the treatment of infections of the skin and skin structure. Dear maybe 204, It is NOT advised that you take both antibiotics at the same time. These two antibiotics are different classifications of antibiotics, however each one only treats certain bacterial infections....neither are able to treat VIRAL infections. Ciprofloxacin is a classification of antibiotic called fluoroquinolones and is used only to treat certain types of urinary tract infections. It works by killing bacteria particularly gram negative infections. Azithromycin is in a class of medications called macrolide antibiotics. This type of antibiotic treats bacterial infections such as bronchitis; pneumonia, STD's ear infections, lung or throat infections or infections of the skin. Azithromycin can treat more types of infections (SOME gram negative and SOME gram positive) but not all.

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