Antimalarials are usually given as one or two pills, once a day. Side effects include vision changes (blurring, halos around lights and sensitivity to light), headache, dizziness, nausea and vomiting. Individuals taking an antimalarial should have eye examinations periodically. Stop hair loss plaquenil Plaquenil pregnancy sjogren's Sir, Antimalarial drugs are well known to be contraindicated in psoriasis 1. In particular, when utilized in psoriatic arthropathy, they have been reported to induce pustular eruption 2, erythroderma 3 and pustular psoriasis 4. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. The use of Plaquenil may cause a severe flare of psoriasis. Unless you are directed to do so by your doctor, do not take Plaquenil, the most commonly prescribed antimalarial. Plaquenil used for psoriasis Plaquenil and Psoriasis -, Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria Plaquenil dosis The use of Plaquenil may cause a severe flare of psoriasis. Some antimalarials can cause the skin disease to get worse in some individuals. Talk to your doctor about the available antimalarial treatments and alternatives. DMARDs & Psoriatic Arthritis National Psoriasis Foundation. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Plaquenil Use in Autoimmune Diseases. Jan 01, 2020 Worsening of psoriasis and porphyria Use of Plaquenil in patients with psoriasis may precipitate a severe attack of psoriasis. When used in patients with porphyria the condition may be exacerbated. The preparation should not be used in these conditions unless in the judgment of the physician the benefit to the patient outweighs the possible hazard. Antimalarials Plaquenil, Quinacrine, chloroquine and hydroxychloroquine may cause a flare of psoriasis, usually two to three weeks after the drug is taken. Hydroxychloroquine is the least likely to cause side effects. Ultraviolet light is contra-indicated for patients with lupus, and prednisone is relatively contra-indicated for psoriasis. This is a case where Plaquenil likely triggered new-onset psoriasis in a patient who was genetically susceptible.