Advice should be individually optimized to achieve a high degree of protection and compliance. Individual risk assessment takes into consideration the duration of stay in the endemic area, the individual exposure, the seasonal transmission rates, and the drug-resistance situation. Maqular degeneration plaquenil Plaquenil and acid refux Long term use of chloroquine can affect the eyes, leading to patchy vision. Eye examinations and blood tests may be necessary for those on very long term chloroquine. Those with kidney or liver disease should be assessed carefully before taking this medication. ARALEN ® CHLOROQUINE PHOSPHATE, USP For Malaria and Extraintestinal Amebiasis DESCRIPTION ARALEN, chloroquine phosphate, USP, is a 4-aminoquinoline compound for oral administration. It is a white, odorless, bitter tasting, crystalline substance, freely soluble in water. ARALEN is an antimalarial and amebicidal drug. These patients are also at risk of developing chloroquine retinopathy. Irreversible visual impairment resulting from accumulation of chloroquine in the retina is a recognized complication of long-term, high-dosage therapy. Total lifetime exposure to chloroquine should not exceed 100g of the base. Exposure-prevention methods may be combined with standby treatment in lower transmission areas if the traveler has been trained to take the antimalarials appropriately. Methods for prevention of exposure may help reduce the reliance on chemoprophylactic drugs. Long term chloroquine prophylaxis Chloroquine Assessment of Long-Term Health Effects of Antimalarial., ARALEN CHLOROQUINE PHOSPHATE, USP Label Dizziness on plaquenil Side Effects. Drug information provided by IBM Micromedex Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Chloroquine Oral Route Side Effects - Mayo Clinic. WHO Model Prescribing Information Drugs Used in Parasitic.. Long-Term Travelers & Expatriates - Chapter 9 - 2020 Yellow Book.. Medscape - Indication-specific dosing for Aralen, Chloroquine phosphate chloroquine, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Ongoing treatment 500mg chloroquine salt 300mg base taken daily for 12 days. Hydroxychloroquine HCQ is nearly identical in structure to CQ and has a similar mechanism of action and therapeutic efficacy in rheumatological and infectious diseases. Like CQ, it also has a long half-life, and a very high volume of distribution. Chloroquine is used for the prophylaxis of malaria in areas of the world where the risk of chloroquine-resistant falciparum malaria is still low. It is also used with proguanil when chloroquine-resistant falciparum malaria is present. However, this combination may not be ideal.