This fungus mainly grows in the central, southeastern, and mid-Atlantic states. Most cases of histoplasmosis don’t require treatment. Estradiol plaquenil combination Plaquenil coffee Hydroxychloroquine pill identification 347 Do you have to be weaned off of plaquenil Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage is also based on weight. The lungs are the primary site of histoplasmosis disease, but the infection can spread to many parts of the body. In Olson's study, 46 percent of the patients had severe disseminated disease beyond the lungs. Olson encouraged rheumatoid arthritis patients and physicians to be alert to the possibility of histoplasmosis infection. Histoplasmosis occurs in patients with rheumatoid arthritis RA who receive corticosteroid therapy, disease modifying antirheumatic therapies such as methotrexate, and has been reported in post-marketing surveillance of patients receiving anti-tumor necrosis factor TNF therapy 4. The disease may progress and spread to other areas of the body. However, people with weaker immune systems may experience serious problems. Hydroxychloroquine with histoplasmosis Medications that Weaken Your Immune System and Fungal., Histoplasmosis in Rheumatoid Arthritis Patients Hydroxychloroquine tablets ip 200 mg uses RESEARCH ARTICLE Open Access Histoplasmosis infection in patients with rheumatoid arthritis, 1998-2009 Timothy C Olson, Tim Bongartz, Cynthia S Crowson, Glenn D Roberts, Robert Orenstein and Eric L Matteson* RESEARCH ARTICLE Open Access Histoplasmosis infection in.. Histoplasmosis infection in patients with rheumatoid.. Hydroxychloroquine Uses, Dosage & Side Effects -. Disseminated histoplasmosis is when the infection progresses and spreads outside the lungs and throughout the body affecting multiple organs and causing severe illness. This usually occurs only in people who have a lowered immunity. The most common symptoms of disseminated histoplasmosis are A 61-year-old truck driver developed a fever, cough, and shortness of breath requiring oxygen support and antibiotics. He had rheumatoid arthritis controlled with methotrexate and hydroxychloroquine. His occupation required delivering produce to and from the Mississippi River Valley to Ontario, Canada. Histoplasmosis is an endemic fungal disease with diverse clinical presentations. Histoplasmosis-associated hemophagocytic lymphohistiocytosis HLH is a rare disorder with limited data regarding treatment and outcome. We described the clinical features, treatment, and outcomes of five patients in our institution with histoplasmosis-associated HLH.