Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Test done before plaquenil Is chloroquine injection safe in early pregnancy How does h-chloroquine work for rheumatoid arthritis Id 10 code for plaquenil Recurrent thoughts of death or suicide; Clinical depression may not be recognized in people with lupus because its symptoms and the symptoms of active lupus can be so similar. For example, lack of energy, trouble sleeping, and diminished sexual interest can be attributed to the lupus itself. However, these are also symptoms of clinical depression. I have been on plaquenil since October of 2013. I started on 50 mg to avoid side effects then upped to 100 and finally to 150. I did experience the GI side effects but they have mostly passed. I do have horrible constipation though and I am not sure if this is due to the plaquenil or to the disease itself. All I know is its a new symptom for me. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil and suicidal thoughts Anxiety, Plaquenil, and Lupus -, Plaquenil causing mood changes and depression? Plaquenil and methylprednisoloneWhere can i buy plaquenilPlaquenil side effects when starting View detailed reports from patients taking plaquenil who experienced heart rate increased. Reports are from official medical reports as well as online extractions from user reviews and forum discussions. Hydroxychloroquine Sulfate Heart Rate Increased Reports.. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Will you have Suicidal ideation with Plaquenil - eHealthMe. Rather than put you on Cellcept, it makes far more sense to up your steroids 5 mg. And if Plaquenil isn't working, most docs STOP IT. It doesn't work for some patients. It didn't for me and I tried it 2X and 1X even Atabrine that turned me yellow. Cellcept is a BIG GUN drug, usually reserved for when patients fail on other stuff. A history of suicidal thoughts or behaviors—Lexapro can increase the risk of suicidal thinking and behavior, especially in children, teens, and young adults. Anxiety, depression and suicidal ideation in patients with rheumatoid arthritis in use of methotrexate, hydroxychloroquine, leflunomide and biological drugs. Pinho de Oliveira Ribeiro N1, Rafael de Mello Schier A, Ornelas AC, Pinho de Oliveira CM, Nardi AE, Silva AC.