Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Hydroxychloroquine interactions with alcohol Chloroquine structure Plaquenil’s long half-life in the body can cause irreversible and progressive damage, Dr. Fung said. Similarly, one study reported that 16 women who’d taken hydroxychloroquine or chloroquine, or a combination of the agents, showed no improvement seven years after stopping drug therapy, and progression occurred in six of the cases. 2 Fortunately, the problems seen by people taking this medication are usually very mild. Serious side effects are rare. Overall, most people who have any noticeable side effects from hydroxychloroquine experience diarrhea or nausea. These usually get better after the person adjusts to the medication, and taking the drug with food can help, as well. I started taking Plaquenil, and I'm supposed to be taking two 200mg pills a day, but I'm only taking one for a week to ease into it. So far I've woken up every morning very nauseous and with a lot of stomach pain and fatigue early in the day plus diarhea. I heard the side effects go away after a. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Side effects taken plaquenil Let me tell you what weaning down from Plaquenil is like., RA and Hydroxychloroquine How Effective is it for Rheumatoid. Does plaquenil help with allergies But take this advice Don’t ignore changes in vision. While side effects of corticosteroids are usually to blame, there is also the possibility of ocular damage associated with long-term use of the antimalarial drugs hydroxychloroquine brand name Plaquenil® and chloroquine. Protecting your eyesight when taking Plaquenil Lupus.. Plaquenil Side Effects Go Away? DailyStrength. Plaquenil & Weight Gain/Loss. If common side effects do occur, they are usually minor and last only for a short period of time. Please note the rare side effects listed below, specifically retinopathy, which causes damage to the eyes. Side effects associated with Plaquenil are placed in three categories common, less common, and rare. Plaquenil Side Effects by Likelihood and Severity INFREQUENT side effects. If experienced, these tend to have a Severe expression. A Disorder Of The Retina Of The Eye;. RARE side effects. If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage.