Chloroquine for lung cancer

Discussion in 'Hydroxychloroquine 200 Mg Tab' started by easy-forex, 28-Feb-2020.

  1. Gangstas New Member

    Chloroquine for lung cancer

    Note: based on a RGCC chemosensitivity analysis I have seen at a German clinic, Hydroxychloroquine has been effective in killing the cancer cells of 5 out 7 patients that were tested. It is one of very few available drugs that inhibits autophagy, a mechanism associated with its anticancer properties.

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    Chloroquine is an established antimalarial agent that has been recently tested in clinical trials for its anticancer activity. The favorable effect of chloroquine appears to be due to its ability to sensitize cancerous cells to chemotherapy, radiation therapy, and induce apoptosis. If you have non-small cell lung cancer and can’t have surgery, this treatment may be an option. Your doctor guides a thin needle through your skin until it touches the tumor inside your lung. Chloroquine, a drug that has historically been used to treat malaria, has recently been combined with a new drug, Tarceva, which kills lung cancer cells. Tarceva only works for some patients, and the cancer almost always becomes resistant after prolonged exposure to the drug.

    In cancer, authophagy is the process used by cancer cells to “self-eat” in order to survive. Specifically, if authophagy is prolonged this will become a lethal process to cancer. duing chemotheraphy, radiotheraphy, etc.) authophagy is used by cancer cells to survive. However, note that Chloroquine has other properties as well that may be very well related to anti cancer mechanism, such as zinc ionophore, and others (see below the section on mechanisms).

    Chloroquine for lung cancer

    Chloroquine in Cancer Therapy A Double-Edged Sword of., Lung Cancer Treatment Options -

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    Indeed, current clinical trials are trying to use chloroquine or hydroxychloroquine, alone or in combination with other drugs to inhibit autophagy during breast cancer therapy since chemotherapy and radiation, regimens that are used to treat breast cancer, are known to induce autophagy in cancer cells. The anti-authophagy drug chloroquine may be a unique way to resensitize some cancer patients to treatment. Chloroquine as an Anti-autophagic Radiosensitizing Drug in Stage I-III Small Cell Lung Cancer Chloroquine The safety and scientific validity of this study is the responsibility of the study sponsor and investigators.

  4. Dimons8 Well-Known Member

    Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Hydroxychloroquine MedlinePlus Drug Information Experts debate hydroxychloroquine dosing guidelines in lupus Lupus Patients Find 2mg Hydroxychloroquine Tablets Forms Needed to.
  5. Alillsainee New Member

    Hydroxychloroquine toxicity - EyeWiki Hydroxychloroquine Plaquenil and chloroquine cause ocular toxicity to various parts of the eye such as the cornea, ciliary body, and retina. Chloroquine can also induce cataract formation; however, no reports of hydroxychloroquine and cataract have been reported 1.

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