Is there anyone who take plequenil and suffers from neuropathy? I take plequenil for a week and it seems like it make my neuropathy so bad and I read that plequenil can cause neuropathy. I had neuropathy caused by a side effect from Cyclosporine when taken two years ago. Chloroquine autophagy off target Discoid lupus plaquenil Hydroxychloroquine 12.5mg The drug may be used to treat a type of blood disease called porphyria cutanea tarda, although it's only used in certain cases because it can worsen symptoms. Plaquenil is in a class of medicines known as antimalarials. It's a less toxic version of the older antimalarials, including quinine and chloroquine. Often plaquenil side effects do go away after a few weeks if you persist with the drug. Plaquenil is the only drug i have EVER had side effects to. I lost my appetite, had slightly blurred vision, had worsening peripheral neuropathy, felt nervous and anxious. I was ready to.took a good three weeks. Plaquenil is a slow-acting drug, meaning that it can take up to 6 months to experience the full benefits of this medication, but it is possible for symptoms to improve in as few as 1 or 2 months. Plaquenil and other antimalarials are the key to controlling lupus long-term, and some lupus patients may be on Plaquenil for the rest of their lives. Is there any possibility of this medication also causing neuropathy? I am now on Plaquinel and am beginning to feel some pain in my feet. Can plaquenil worsen neuropathy NAME OF MEDICATION COMMON BRAND NAMES USED TO TREAT, Can Plaquenil cause Peripheral Neuropathy? Chloroquine rheumatoid arthritis mechanism of actionIs plaquenil used to treat fibromyalgiaPlaquenil skin rash pictures The latter is related to drug accumulation in melanin-rich tissues. 15,16 Prolonged treatment with chloroquine also can cause toxic myopathy, cardiopathy, and peripheral neuropathy and neuropsychiatric disturbances; all of these reactions improve if the drug is discontinued promptly. 17,18 Both chloroquine and hydroxychloroquine should be used. Effectiveness of Chloroquine and Hydroxychloroquine in Treating.. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Hydroxychloroquine Sulfate Neuropathy Peripheral Reports.. Severe weakness with respiratory failure is a serious and common complication of critically ill patients in the intensive care unit setting. Recent studies have elucidated 2 entities characterized by severe weakness that occur as a result of these circumstances critical illness neuropathy and. PLAQUENIL is indicated for the treatment of chronic discoid lupus erythematosus and systemic lupus erythematosus in adults. Rheumatoid Arthritis. PLAQUENIL is indicated for the treatment of acute and chronic rheumatoid arthritis in adults. CONTRAINDICATIONS. Use of PLAQUENIL is contraindicated in patients with known hypersensitivity to 4 Jan 25, 2010 There is a possibility that Plaquenil may affect nerve conduction. Given your history I would make an appointment to see your doctor. You might want to click on the Drugs A to Z tab at the top of this page. You can find out lots of information on peripheral neuropathy.