Most people develop psoriasis first and are later diagnosed with psoriatic arthritis, but the joint problems can sometimes begin before skin patches appear. Joint pain, stiffness and swelling are the main signs and symptoms of psoriatic arthritis. Methotrexate and hydroxychloroquine for rheumatoid arthritis Chloroquine treatment lysosome Plaquenil brand name vs generic The anti-malarial drug hydroxychloroquine Plaquenil may help, but it usually is avoided as it can cause a flare of psoriasis. Azathioprine Imuran may help those with severe forms of psoriatic arthritis. For severely swollen joints, corticosteroid injections can be useful. Surgery can be helpful to repair or replace badly damaged joints. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Summary. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. In both psoriasis and psoriatic arthritis, disease flares may alternate with periods of remission. They can affect any part of your body, including your fingertips and spine, and can range from relatively mild to severe. Can plaquenil cause psoriatic arthritis Inflammatory Osteoarthritis And Plaquenil, Hydroxychloroquine Plaquenil Hydroxychloroquine copay cardEffect of plaquenil on free light chains Plaquenil is sometimes prescribed to treat inflammation in people with psoriatic arthritis. Plaquenil is also known by its drug name, Hydroxychloroquine. Plaquenil should be used with caution in people with skin symptoms of psoriasis since it can cause a severe flare-up. Plaquenil Hydroxychloroquine MyPsoriasisTeam. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Plaquenil for Psoriatic Arthritis? - Psoriasis - Inspire. Some antimalarials can cause the skin disease to get worse in some individuals. Talk to your doctor about the available antimalarial treatments and alternatives. Corticosteroids. Steroid medications taken by mouth or injection are not generally recommended for long-term treatment of psoriatic arthritis. However my rheumatologist took me off all arthritis drugs and we added them back little by little. When plaquenil was finally included with the other drugs again, it took about three days and my My face started swelling and the rash and and itching. I can only assume that this was the cause of my allergic reaction, even after all the years of use." They're painkillers that ease joint pain and swelling from psoriatic arthritis. But they also can trigger psoriasis flare-ups. Aralen and hydroxychloroquine Plaquenil can cause problems.