B, Brown pigmentation on the legs in another patient who had systemic lupus erythematosus associated with diffuse discoid lupus. The skin biopsy was performed on the brown area distant from discoid lesions. Eye doctors for plaquenil screening Methylene blue falciparum target chloroquine Plaquenil and itchy eyes Updated recommendations on the use of hydroxychloroquine in dermatologic practice Previously presented This work was presented in part at the annual meeting of the American Academy of Dermatology in Washington, DC, March 4-7, 2016, and the Alabama Dermatology Association Dermatology Summer Symposium in Destin, Florida, June 23-26, 2016. An elderly woman presented with 6 months history of skin coloured to erythematous papules in annular pattern over extremities, upper back and neck. The patient was diagnosed with granuloma annulare GA and started on hydroxychloroquine HCQ 300 mg daily. After 4 months of treatment, she developed bluish grey pigmentation within the plaques of GA with normal surrounding skin figure 1A,B. Hydroxychloroquine-induced pigmentation lesions usually begin after a few months or years of treatment. When we compared our patients with the controls, we found no significant association with the duration of HCQ treatment or with the cumulative dose of HCQ. B, Presence of iron in the same areas of the dermis (Perls staining, original magnification ×100). Pub Med Google Scholar Crossref Morrison LK, Nordlund JJ, Heffernan MP. Pub Med Google Scholar Costedoat-Chalumeau N, Galicier L, Aumaître O, et al; Group PLUS. Google Scholar Costedoat-Chalumeau N, Amoura Z, Hulot JS, et al. Pub Med Google Scholar Crossref Costedoat-Chalumeau N, Leroux G, Piette J-C, Amoura Z. A, Interstitial and perivascular brown pigmented granules in the dermis (hematoxylin-eosin-safran staining, original magnification ×100). Woman in grey hydroxychloroquine-induced hyperpigmentation Skin Pigmentation with Hydroxychloroquine Plaquenil., Hydroxychloroquine induced cutaneous pigmentation a unique. Methotrexate and folic acid and plaquenil for lupusRetinal toxicity from chloroquine apre-19 cellsHydroxychloroquine vs hydroxychloroquine sulfateIcd 10 plaquenil An African American woman, aged 50 years, presents with painless “bruises” on her leg. with a blue-black to gray. Francès C, Piette J-C, et al. Hydroxychloroquine-induced pigmentation. Painless, bruise-like hyperpigmentation on a woman with lupus.. Hydroxychloroquine-Induced Pigmentation in Patients With.. Acquired Hemochromatosis with Pronounced Pigment Deposition.. Women who are 100% gray often wear their hair short. But consider long layers. They can be beautiful and add movement to healthy, bouncy hair. Swipe to advance. Up Next Next Slideshow Title. Description The authors illustrate the case of a woman in her 80s with history of systemic lupus erythematosus and Sjögren syndrome. She had lost medical follow-up with her rheumatologist in the last 3 years due to progressive functional and cognitive impairment but she was still taking prednisolone 5 mg per day and hydroxychloroquine 400 mg per day for, at least, the past 11 years. Hydroxychloroquine-Induced Pigmentation in Patients With Systemic Lupus Erythematosus A Case-Control Study JAMA Dermatol, July 3, 2013. Full text $30. Twenty-four patients with systemic lupus erythematosus developed pigmentation after treatment with hydroxycloroquine for a median of 6.1 years. Most patients reported that the pigmented lesions.