Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil for lupus mechanism Flomax and plaquenil Natural substitute for chloroquine Retinal toxicity from plaquenil 2019 Hi, I've been diagnosed with Hashimoto's for about 8 months now. My TSH at it's highest was 8. My antibodies were pretty high. I've been on a variety of meds and nothing seemed to really help me. Nov 11, 2008 I would get with the endo as many have suggested. I always try to get a cortisol test and ACTH stim along with the thyroid tests to see if something else is going on and figure out which med needs best be adjusted. I do think the plaquenil helps my thyroid some being an immunosuppressant but this is my gut feeling. Thyroid diseases is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years, also take medication Enbrel, and have Osteoporosis Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil effect on thyroid Plaquenil Hydroxychloroquine - Side Effects, Dosage., Increasing plaquenil, having problems New guidelines for hydroxychloroquine macuopathy 2018 pubmed The plaquenil has caused a weight gain of about 20-25 pounds for me. Since I was diagnosed with MCTD a year ago, Plaquenil has been the only medication besides eye supplements, thyroid meds - been stable for years, and most recently Evoxac that I have been given. Plaquenil & Weight Gain/Loss -. Will you have Thyroid diseases with Plaquenil - eHealthMe. Thyroid Disease and Arthritis How They're Connected. The aforementioned rare side effect that affects vision hydroxychloroquine retinopathy, if caught early, may improve after discontinuation of Plaquenil. Since the side effect of vision loss is possible but rare, it is important for you to tell your doctor about any vision changes that you experience. I also decreased my Plaquenil dosage it had been increased for a short period and that also helped my situation. As for you, I couldn't say if the Plaquenil is the cause for your changing symptoms as it takes quite a while to see the effects of that medication 6 months or so. Feb 19, 2020 Our Plaquenil hydroxychloroquine Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.