One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Retinal thickness changes plaquenil toxicity Plaquenil long term Plaquenil positive reviews Researchers suggest that one central point in both eyes indicates toxicity and one should have a low threshold with regards to any defects. 19 The misinterpreted visual field defect using the larger testing strategies could potentially delay the diagnosis of Plaquenil toxicity resulting in irreversible vision loss. Due to the possibility of. Of course the aim is avoid drug related retinal toxicity, which on ophthalmic examination, appears as the classic Bull’s eye change affecting the macula. Once retinal toxicity from hydroxychloroquine occurs, it is thought that the retinal changes are permanent and the disease can progress even if hydroxychloroquine is stopped for 1 to 3 years. Color Testing n!Ishihara color plates n!Contributes in diagnosis, but not suitable for ruling out toxicity n!Lacks sensitivity and specificity Amsler Grid n!Contributes in diagnosis, but not suitable for ruling out toxicity n!Inconsistent sensitivity for maculopathy n!Fairly nonspecific, must exclude alternate/ concomitant disease It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Color dx test in plaquenil toxicity A New Objective Parameter in Hydroxychloroquine-Induced., My Take on New Ocular Screening Guidelines for Plaquenil. Is hydroxychloroquine a nsaidChloroquine aralen side effectsSjoren how help plaquenilHydroxychloroquine rx coupon Aug 29, 2014 Plaquenil, hydroxychloroquine HCQ, is an anti-malarial medication that has been proven to be useful in the treatment of patients with rheumatoid arthritis RA, systemic lupus erythematosus SLE and other inflammatory and autoimmune diseases. The Risk of Retinal Toxicity with Plaquenil. Chloroquine and Hydroxychloroquine Maculopathy Case.. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Chloroquine and hydroxychloroquine belong to the quinolone family. They are related drugs with similar clinical indications for use and similar manifestations of retinal toxicity, although their therapeutic and toxic doses differ. Aug 01, 2009 After seeing MANY professionals including a neurologist, a retinal specialist, neuro-ophthalmologist, and undergoing MANY different tests, she was diagnosed with Plaquenil toxicity. She does have field of vision loss, mostly on things that are close up. She took Plaquenil for almost five years before having any symptoms. Nov 18, 2011 Keywords hydroxychloroquine toxicity, Plaquenil, toxic maculopathy, Humphrey visual field, retinal toxicity, automated perimetry Introduction Misinterpretation of Humphrey visual field HVF findings in patients utilizing hydroxychloroquine HCQ can lead to delay in diagnosis of retinal toxicity.