In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. Plaquenil itching Hydroxychloroquine retinopathy screening guidelines While there is good clinical evidence demonstrating the drug’s efficacy in rheumatoid arthritis and lupus, there are very few studies looking at hydroxychloroquine as a treatment for Sjögren’s. The studies that do exist show mixed results some show benefit and some show no benefit. New Treatment Guidelines for Sjo¨gren’s Disease 535. treatment. This process involves the assessment of key ocular symptoms as described previously, as well as the examination of several objective parameters, including tear production, tear film stability, tear osmolarity, lid margin disease, and ocular surface damage. Alternatives to Plaquenil I'm not yet diagnosed but my rheumatologist has said probable SLE and probable Sjogren's. A few weeks ago I was out in the sun for 10 minutes and developed a rash all over my feet and legs and flared up the next day. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. Alternatives to plaquenil for sjogrens Plaquenil for treating Sjogren's Syndrome Treato, New Treatment Guidelines for SjOgren's Disease Hydroxychloroquine chronic fatigue The news has been buzzing about Venus Williams dropping out of the US Open because of Sjogren's syndrome. As the media has discussed, Sjogren's is an autoimmune disease that attacks the tear and salivary glands and generally results in widespread dryness in the body. In addition to dry eyes and. Why There's More to Sjogren's Syndrome The Dr. Oz Show. Healthboards - Immune & Autoimmune - Lupus Alternatives to. Plaquenil Compared to Alternatives -. Hello! Here is a short list Prednisone, Imuran, Remicade, Methotrexate Later sidesteps Prednisone's side effects, which include weight gain, mood swings, diabetes and eye problems, such as cataracts. I hope this was helpful enough. Sjogrens Syndrome treatment, vitamins, herbs and supplements, natural and alternative treatment June 17 2018 by Ray Sahelian, M. D. Sjogren's syndrome is an autoimmune disease that attacks the body's moisture-producing glands, leading to progressively worsening dry mouth, eyes, vagina and skin, as well as fatigue. For many patients with Sjogren's, Plaquenil hydroxychloroquine has long been the go to drug that their doctors prescribe. It is often the first line of attack before other more aggressive therapies are added such as methotrexate or rituximab that have bigger impacts on the immune system.