Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Plaquenil blindness Plaquenil reviews side effects Is there a generic for hydroxychloroquine The present study was aimed to find out the protective effect of quercetin on hepatotoxicity resulting by commonly used antimalarial drug chloroquine CQ. Swiss albino mice were administered with different amounts of CQ ranging from human therapeutic equivalent of 360 mg/kg body wt. to as high as 2000 mg/kg body wt. We observed statistically significant generation of reactive oxygen species. Uses of Chloroquine It is used to treat or prevent malaria. It is used to treat a type of bowel infection. It may be given to you for other reasons. Chloroquine is used to prevent or treat malaria caused by mosquito bites in countries where malaria is common. Malaria parasites can enter the body through these mosquito bites, and then live in body tissues such as red blood cells or the liver. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Chloroquine in liver Chloroquine inhibits hepatocellular carcinoma cell growth., Chloroquine Indications, Side Effects, Warnings - Reducing plaquenil Chloroquine feeding resulted in tumors located in the liver lymphosarcomas and primaquine in tumors in the kidney histiocytic sarcomas. Toads fed chloroquine plus primaquine developed tumors in the liver, kidney, lung, and urinary bladder, and all the tumors were diagnosed as histiocytic sarcomas. Chloroquine C18H26ClN3 - PubChem. Chloroquine Oral Uses, Side Effects, Interactions.. Chloroquine - FDA prescribing information, side effects.. Chloroquine needs to be taken 1-2 weeks before traveling to an area with malaria, compared to some alternatives that can be taken 1-2 days before. chloroquine is only effective against malaria from certain areas of the world. chloroquine may worsen psoriasis, seizures, hearing problems, and liver conditions. The purpose of this study is to test the hypothesis that chloroquine will reduce the ability of ductal carcinoma in situ DCIS to survive and spread. Participants will receive either chloroquine standard dose 500mg/week or chloroquine low dose 250mg/week for 1 month prior to surgical removal of the tumor. Chloroquine reduces liver injury in the early reperfusion phase, but worsens liver injury during the late reperfusion phase after hepatic ischemic injury. To determine whether chloroquine treatment could affect liver I/R injury, chloroquine was administrated to rats 1 h before warm ischemia followed by a daily injection for up to 2 days.