The fatigue may worsen with physical or mental activity, but doesn't improve with rest. This condition is also known as systemic exertion intolerance disease (SEID) or myalgic encephalomyelitis (ME). The cause of chronic fatigue syndrome is unknown, although there are many theories — ranging from viral infections to psychological stress. 2016 ophthalmology journal hydroxychloroquine How does plaquenil treat lupus Plaquenil hydroxychloroquine is a medication that has been used for many years to help musculoskeletal symptoms and fatigue in patients with autoimmune conditions such as rheumatoid arthritis, lupus and Sjögren’s. While there is good clinical evidence demonstrating. Viral CFS- A Possible Cure - MY STORY. I took Plaquenil for my chronic hives for several years. Finally, I stopped the Plaquenil, and the hives never came back. Ahouse18. New Member. Joined Mar 2014. I have Kaiser insurance and they don't treat Chronic Fatigue Syndrome, so I went to a doctor on the peninsula that specializes in Chronic. Myalgic encephalomyelitis/chronic fatigue syndrome ME/CFS is a serious, long-term illness that affects many body systems. People with ME/CFS are often not able to do their usual activities. At times, ME/CFS may confine them to bed. People with ME/CFS have severe fatigue and sleep problems. There's no single test to confirm a diagnosis of chronic fatigue syndrome. Some experts believe chronic fatigue syndrome might be triggered by a combination of factors. Plaquenil and chronic fatigue syndrome Is extreme fatigue a side effect of Plaquenil?, Viral CFS- A Possible Cure - MY STORY Plaquenil oct maculaPlaquenil staggered dose In some patients it may be caused by fibromyalgia, a syndrome of widespread muscle pain and fatigue. About one-third of people with lupus have fibromyalgia. In other cases, the fatigue can be caused by another condition, such as anemia or depression. Fatigue can also be a side effect of medication. Fighting Lupus Fatigue and Boosting Energy. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome ME/CFS.. Link between Fibromyalgia Fatigue & Chronic Fatigue.. Chronic fatigue syndrome CFS is a complicated disorder characterized by extreme fatigue that can't be explained by any underlying medical condition. The fatigue may worsen with physical or mental activity, but doesn't improve with rest. Jun 11, 2007 Hopefully the Plaquenil will help with your fatigue, it did with mine. I don't know how long you have been taking it but it can take 6+ months before you notice a lot of improvement. For me the fatigue was very hard to deal with and it's something I talked to my rheumy about. She said it is the number one complaint of people with Lupus or. Plaquenil hydroxychloroquine "I have been on this medication for approximately 8 years. Before I started this medicine I was in terrible shape. With Sjogren's syndrome as my primary autoimmune disease and rheumatoid arthritis as my secondary autoimmune disease I was in terrible persistent pain.