Other times though, the cause of the shedding locks could be the medications used to treat arthritis. Fortunately, hair loss from arthritis medications is not a widespread complication. Hydroxychloroquine routine diagnostics Chloroquine cancer stem cell Whenever a patient using hydroxychloroquine reports hair loss there are 5 possibilities to consider. 1. The Plaquenil is Causing Hair Loss. One needs to always consider the possibility that Plaquenil is causing the hair loss. Usually Plaquenil related hair loss starts 2-6 months after the Plaquenil was started. Sep 25, 2017 Not only have I lost nearly all my hair, but the quality of the hair has changed from thick glossy healthy hair, to thin wiry brittle hair. I keep being told that plaquenil will help with the hair loss – it hasn’t. I keep reading that plaquenil can cause hairloss, and my rheumatologist tells me otherwise. This whole issue is confusing. Losing Hair on Plaquenil The 5 Possibilities. Hydroxychloroquine also known by its popular brand name Plaquenil is an oral medication that is commonly used to treat a variety of autoimmune diseases including systemic lupus, dermatomyositis, rheumatoid arthritis, Sjogren’s and many other conditions as well. Methotrexate: The most commonly prescribed disease-modifying antirheumatic drug (DMARD) for rheumatoid arthritis, methotrexate is responsible for hair loss in about 1 to 3 percent of people. Still, if your hair is an important part of your identity, it’s not a small matter to you. Is plaquenil hair loss permanent Immune & Autoimmune - Lupus Plaquenil side effect hairloss, Tips to Prevent Hair Loss in Lupus Patients Chloroquine tablets bootsChloroquine reviewsPlaquenil retinopathy to reverse Generally as a drug-related side effect, hair loss is not drastic and the hair does not fall out in patches. And it usually grows back after you stop taking the drug. But if you have inherited male or female pattern baldness, arthritis medications could trigger or accelerate such permanent hair loss. Arthritis Medications and Hair Loss Arthritis Foundation. Hydroxychloroquine Plaquenil and Hair Loss Is my Plaquenil.. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. Hi aokech, I know exactly what you are talking about. I was on MTX and Prednisone, and still am on Plaquenil and I have had hair loss and thinning for some time now. I have a very good hair dresser and she knows what to do and my hair has started to grow back nicely and is much longer than it used to be. Dec 13, 2012 ~shalyserenee~ said. This post spoke pretty directly to me as I have both been on Plaquenil and have lost all my hair when I was originally diagnosed w Lupus 15 years ago and experienced some serious weight loss while on dialysis and thru the first few month after my kidney transplant alittle less than a year ago. Plaquenil will eventually help your hair loss, but that will be a very slow process over a long period of time since plaquenil builds up in your body pretty slowly. And you should keep your head a scalp protected from the sun as VeeJ said.