Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Plaquenil and diarrhea and weight loss Hydroxychloroquine pediatric dose Plaquenil dosing by weight An overdose of hydroxychloroquine can be fatal, especially in children. Hydroxychloroquine overdose must be treated quickly. You may be told to induce vomiting right away at home, before transport to an emergency room. Ask the poison control center how to induce vomiting in the case of an overdose. Apr 15, 2019 Keywords hydroxychloroquine, blindness, retinal maculopathy, vision impairment, co-morbidity Key Messages The incidence of retinal toxicity in long-term HCQ users in a large US population is low. Nov 16, 2018 CHICAGO – The dosage of hydroxychloroquine HCQ for treating patients with systemic lupus erythematosus SLE is often overly influenced by fear that the drug could cause blindness, Michelle A. Petri, MD, said at the annual meeting of the American College of Rheumatology. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Hydroxychloroquine blindness Plaquenil Hydroxychloroquine - Side Effects, Dosage., Incidence of blindness in a population of rheumatic patients. Adderall and plaquenil weight gain A risk factor for Plaquenil hydroxychloroquine retinotoxicity is a daily dose that exceeds 5.0 mg of drug per kg of body weight. The tool on the right simply calculates this threshold based on a ppatient’s real body weight. It’s important to understand that the daily dose is only one risk factor for plaquenil retinotoxicity. Plaquenil Risk Calculators. Fear of blindness hobbles hydroxychloroquine treatment of SLE.. The Risk of Retinal Toxicity with Plaquenil. CHICAGO – The dosage of hydroxychloroquine HCQ for treating patients with systemic lupus erythematosus SLE is often overly influenced by fear that the drug could cause blindness, Michelle A. Petri, MD, said at the annual meeting of the American College of Rheumatology. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria 2. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. Hydroxychloroquine retinopathy causes destruction of macular rods and cones with sparing of foveal cones. This pattern provides the typical bullseye appearance. RPE migrates into the areas of destructed photoreceptors, causing pigment laden cells to be detected in the outer nuclear and outer plexiform layers.