Chloroquine phosphate resistant malaria

Discussion in 'Canadian Online Pharmacies' started by pat, 14-Mar-2020.

  1. tsukermann User

    Chloroquine phosphate resistant malaria


    -Suppressive therapy should continue for 8 weeks after leaving the endemic area. Approved indication: For the suppressive treatment of malaria due to Plasmodium vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: 300 mg base (500 mg salt) orally once a week Comments: -For prophylaxis only in areas with chloroquine-sensitive malaria -Prophylaxis should start 1 to 2 weeks before travel to malarious areas; should continue weekly (same day each week) while in malarious areas and for 4 weeks after leaving such areas.

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    Chloroquine phosphate is in a class of medicine known as antimalarials and amebicides. There are roughly 300 circumstances of severe malaria in the United States annually, most of them acquired from journey to malaria-endemic nations. Severe malaria must be handled with intravenous IV antimalarial medications. Mar 16, 2020 Chloroquine is an immunosuppressive drug and anti-parasite commonly used in malaria treatment. It’s most often taken as a tablet by mouth. Recently, a WhatsApp voice memo has circulated around. Chloroquine DescriptionChloroquine - Clinical PharmacologyIndications and Usage For ChloroquineContraindicationsWarningsPrecautionsAdverse ReactionsOverdosageChloroquine Dosage and AdministrationHow Is Chloroquine SuppliedReferences

    Approved indication: For acute attacks of malaria due to P vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: Chloroquine-sensitive uncomplicated malaria (Plasmodium species or species not identified): 600 mg base (1 g salt) orally at once, followed by 300 mg base (500 mg salt) orally at 6, 24, and 48 hours Total dose: 1.5 g base (2.5 g salt) Comments: -For the treatment of uncomplicated malaria due to chloroquine-sensitive P vivax or P ovale, concomitant treatment with primaquine phosphate is recommended. 60 kg or more: 1 g chloroquine phosphate (600 mg base) orally as an initial dose, followed by 500 mg chloroquine phosphate (300 mg base) orally after 6 to 8 hours, then 500 mg chloroquine phosphate (300 mg base) orally once a day on the next 2 consecutive days Total dose: 2.5 g chloroquine phosphate (1.5 g base) in 3 days Less than 60 kg: First dose: 16.7 mg chloroquine phosphate/kg (10 mg base/kg) orally Second dose (6 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Third dose (24 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Fourth dose (36 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Total dose: 41.7 mg chloroquine phosphate/kg (25 mg base/kg) in 3 days Comments: -Concomitant therapy with an 8-aminoquinoline compound is necessary for radical cure of malaria due to P vivax and P malariae.

    Chloroquine phosphate resistant malaria

    Chloroquine Resistance in Plasmodium falciparum Malaria., Is Chloroquine a Cure for Coronavirus? Scientists Say Maybe.

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  3. Chloroquine needs to be taken 1-2 weeks before traveling to an area with malaria, compared to some alternatives that can be taken 1-2 days before. chloroquine is only effective against malaria from certain areas of the world. chloroquine may worsen psoriasis, seizures, hearing problems, and liver conditions.

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    Chloroquine, an antimalaria drug of the group of 4-aminoquinolines, works well and effectively as a schizonticidal drug against the erythrocytic forms of all types of plasmodia. Today though, almost all pathogens of the potentially lethal malaria tropica have become resistant to this rather well tolerated, and for many decades, useful medication. Chloroquine Phosphate is the phosphate salt of chloroquine, a quinoline compound with antimalarial and anti-inflammatory properties. Chloroquine is the most widely used drug against malaria, except for those cases caused by chloroquine resistant Plasmodium falciparum. Although the mechanism of action is not fully understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase. The Nigeria Medical Association has debunked claims on social media that chloroquine phosphate is a cure for coronavirus, aka COVID-19, saying the anti-malaria drug is not a proven antidote.

     
  4. defka User

    Some scientists are touting the efficacy of the drug in preliminary studies, but are also noting that much more research needs to be done before confirming or denying it as a potential cure for coronavirus. Chloroquine phosphate where to buy it. REEF2REEF. Chloroquine Indications, Side Effects, Warnings - Chloroquine phosphate REEF2REEF Saltwater and Reef Aquarium.
     
  5. johnsovich Well-Known Member

    This is not a list of all drugs or health problems that interact with chloroquine. Chloroquine Aralen - Side Effects, Dosage, Interactions - Drugs CHLOROQUINE AND PROGUANIL ANTI-MALARIAL TABLETS Atovaquone-Proguanil versus Chloroquine-Proguanil for Malaria.
     
  6. STork Well-Known Member

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    Chloroquine Inhibits Autophagy to Potentiate Antiestrogen.
     
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