It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Plaquenil causes nausea Urinary side effects of hydroxychloroquine Plaquenil side effects from the n eyes I was prescribed plaquenil for Sjogrens about 5 years ago by my rheumatogist. I too was afraid of the side effects and didn't realize that the disease would worsen, so I just didn't take the plaquenil. Two years later I began having pericarditis attacks and wound up in the hospital. Their shins and forearms. The discoloration is now considered to be more likely to occur in thin skin that gets easily traumatized, especially if superficial bleeding occurred in the bruises. This pigmentation gradually fades over many months’ time if the dose of Plaquenil is reduced or stopped. Plaquenil is notoriously a slow-acting drug. Plaquenil is generally well-tolerated, but side effects are possible. Common side effects linked to Plaquenil include nausea and diarrhea. Taking the medication with food eases nausea for most people taking the drug. Less common side effects include skin rashes, hair thinning, and weakness. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Plaquenil stopping Ask the Expert Plaquenil and Sjögren’s, Plaquenil Use in Autoimmune Diseases Chloroquine canadaTreatment of chloroquine resistant falciparum malaria Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria chloroquine-resistant. The United States Center for. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Taking Plaquenil for Rheumatoid Arthritis. Rx Side Effects New Plaquenil Guidelines and More - American Academy.. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking Plaquenil and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Plaquenil is the only drug I am allergic to. I broke out in a rash and was taken off it after two weeks. That was three years ago. I was just Dx with glaucoma and cataracts, all early. This stupid disease is just one thing after another. I have a hard time keeping up with all the doc appointments. If you stop taking the pills in the middle of the month you will have bleeding approximately 2-5 days later, followed by a regular period a couple of weeks later.