Chloroquine prophylaxis in pregnancy

Discussion in 'Canada Drugs' started by bEnGuN, 14-Mar-2020.

  1. svetsid New Member

    Chloroquine prophylaxis in pregnancy


    They are written by UK doctors and based on research evidence, UK and European Guidelines. You may find the Malaria article more useful, or one of our other health articles.

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    Maternal participants receive a therapeutic dose of chloroquine 1,500 mg given over 3 days, 2 tablets on Day 0, 2 tablets on Day 1, 1 tablet on Day 2 administered twice during pregnancy at 20-28 weeks and at 28-34 weeks. Maternal participants receive a therapeutic dose of sulfadoxine-pyrimethamine SP. Previously mefloquine was not recommended for the treatment of malaria in pregnant women. The change in recommendations is based on the recent Food and Drug Administration FDA re-categorization of mefloquine from a pregnancy category C drug to category B, based on their review of the published data on mefloquine use during pregnancy. To determine the effect of chloroquine chemoprophylaxis during pregnancy on birth weights, a randomized trial was carried out in 19 in Banfora, Burkina Faso West Africa.

    Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it.

    Chloroquine prophylaxis in pregnancy

    Malaria Prophylaxis. The ABCD of Malaria Prophylaxis. Patient, Update New Recommendations for Mefloquine Use in Pregnancy

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  3. Two controlled trials of chloroquine prophylaxis during pregnancy were performed, one in Burkina Faso in 1987, on all pregnant women, and the other in Cameroon in 1992, on primigravidae Maternal haematocrit at delivery was found to be significantly higher in those women who had received chloroquine

    • Effect of chloroquine prophylaxis during pregnancy on..
    • Effect of Chloroquine Chemoprophylaxis during Pregnancy on..
    • Chloroquine Use During Pregnancy.

    Chloroquine can be prescribed to adults and children of all ages. It can also be safely taken by pregnant. women and nursing mothers. Who should not take chloroquine? People with psoriasis should not take chloroquine. How should I take chloroquine? Both adults and children should take one dose of chloroquine per week starting at least 1 week. When comparing chloroquine and sulfadoxine-pyrimethamine as intermittent therapy for the treatment of malaria in pregnant women — in a setting of high resistance to sulfadoxine-pyrimethamine. Use in pregnancy. There is no evidence that chloroquine is harmful in prophylactic doses during pregnancy. Because of the susceptibility of pregnant women to falciparum malaria, it should be used at the recommended dosage for both prophylaxis and treatment wherever chloroquine-sensitive malaria is prevalent. Adverse effects

     
  4. charlik2 New Member

    Malaria infection in pregnant women is associated with high risks of both maternal and perinatal morbidity and mortality. Chloroquine Uses, Side Effects & Warnings - Chloroquine Oral Uses, Side Effects, Interactions, Pictures. Chloroquine - an overview ScienceDirect Topics
     
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