One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Plaquenil mayoclinic Eye screening tests for plaquenil guidelines What is plaquenil side effects Can yo freeze reconstituted chloroquine Chloroquine retinopathy, is a form of toxic retinopathy damage of the retina caused by the drugs chloroquine or hydroxychloroquine, which are sometimes used in the treatment of autoimmune disorders such as rheumatoid arthritis and systemic lupus eye toxicity limits long-term use of the drugs. Screening requires the use of tests, such as 10–2 visual fields and SD-OCT and other modern techniques, such as autofluorescence imaging and multifocal electroretinography, to demonstrate early retinal damage.” 1 Melles & Marmor. The Risk of Toxic Retinopathy in Patients on Long-term Hydroxychloroquine Therapy. Published September 15, 2014 Is Damage Still Occurring? Can Plaquenil macular toxicity continue to progress long after the patient stops taking the drug? By Diana L. Schechtman, OD and Paul M. Karpecki, OD It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Plaquenil retina damage Plaquenil Side Effects on Your Eyes and Vision, Plaquenil Risk Calculators Plaquenil genetic risk testSymptoms of eye damage from plaquenilPlaquenil eye exam letter review of optometryHydroxychloroquine lupus mechanismNbme 15 chloroquine Your ophthalmologist may use these tests to look for retina damage from Plaquenil Visual field test During this test you sit down and look into a bowl-like machine. OCT imaging This test makes a detailed, three-dimensional image of your eye. Multifocal ERG This test looks at cells in the. How Do Ophthalmologists Look for Plaquenil Damage.. Is Damage Still Occurring? - Review of Optometry. Conditions Plaquenil-related Eye Problems Eugene Eye Care. Aug 14, 2017 Retinal Damage. According to Drugs.com, Plaquenil given for a long term can cause retinal disorders after a few months or years of daily use--especially if the dose exceeds 400mg per day. The risk of retinal damage increases at doses of 600mg to 700mg. Plaquenil toxicity is typically asymptomatic in early stages, but over time can lead to severe vision loss and retinal damage. The risk of retinal toxicity was initially believed to be less than 1% after long-term or a cumulative dosage of 1,000mg. 3 The toxicity would double by 10 years, resulting in a 20% prevalence after 20 years. 4. Plaquenil-induced toxicity usually will not occur before five years of taking the drug. “Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so the medication can be stopped if toxicity occurs.