It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Plaquenil alternatives uctd Chloroquine phosphate how long do side effects last Plaquenil not sleeping Hydroxychloroquine quinine Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. However, risk increases with duration of use. The average dose is 400 mg. per day. This is a very safe dose. Retina related complications have been reported at this dosage level too. However, the risk is much less than higher doses. Even at higher doses, the incidence of complications is not common. As long as you see your eye care professional regularly, you can feel confident that the plaquenil is safe. Common Plaquenil side effects may include headache, dizziness, ringing in your ears; nausea, vomiting, stomach pain; loss of appetite, weight loss; mood changes, feeling nervous or irritable; skin rash or itching; or. hair loss. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil eye risks Taking Plaquenil for Rheumatoid Arthritis, Conditions Plaquenil-related Eye Problems Eugene Eye Care Difficulty sleeping side effect of plaquenilDoes plaquenil affect the brain fog Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Plaquenil Side Effects Common, Severe, Long Term -. Plaquenil Uses, Dosage & Side Effects -. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Uncontrolled eye movements unsteadiness, trembling, or other problems with muscle control or coordination vomiting Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. The risk is lower with a lower dose however there is no true safe dosage for longer duration of use. Another study of 4000 patients found a prevalence of 6.8/1000 patients 8. Risk factors that increase the chance of hydroxychloroquine retinopathy include daily dosage, cumulative dose, renal or liver disease, age, and previous retinal disease 9. Plaquenil Side-Effects. What is Plaquenil and how does it affect your eyes? Plaquenil Hydroxychloroquine is a medication that is used often to treat conditions such as Rheumatoid Arthritis, Lupus Sarcoidosis, and additional autoimmune disorders. Plaquenil has been known to cause retinopathy or damage to the retina.